Channel Proteomes

Protein

Q8R0S4 – Cav beta-4

Cav2 Nano-Environments

Protein Details

Full Name Voltage-dependent L-type calcium channel subunit beta-4
Sequence Length 519 AA
Molecular Weight 57,950 Da
Topology cytosolic
Subcellular Location plasma membrane
Biochemical Function ICT
UniProt Q8R0S4

Antibody-Dependent Co-Purification

Solubilization Buffer
Antibody Group CL-91
Anti-Cav2.1
Anti-Cav2.2
Anti-Cav2.3
Anti-CavBeta1
Anti-CavBeta2
Anti-CavBeta3
Anti-CavBeta4

Abundance in Anti-Cav2 APs (relative to Cav2 alpha 1)

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Subtype Preference

Preference for association of Cav beta-4 with specific Cav2 alpha 1 subunits.

Subtype Preference Chart

Sequence Coverage

Coverage is 68.2% absolute, 87.8% relative. Sequence length is 519 AA. 337 of 386 AA found within and 17 of 133 AA found outside of common MS mass range.

1
51
101
151
201
251
301
351
401
451
501
MSSSYGKNGA ADGPHSPSSQ VARGTTTRRS RLKRSDGSTT STSFILRQGS
ADSYTSRPSD SDVSLEEDR
E AIRQEREQQA AIQLERAKSK PVAFAVKTNV
SYCGALDEDV PVPSTAISFD AK
DFLHIKEK YNNDWWIGRL VKEGCEIGFI
PSPLR
LENIR IQQEQKRGRF HGGKSSGNSS SSLGEMVSGT FRATPTTTAK
QK
QKVTEHIP PYDVVPSMRP VVLVGPSLKG YEVTDMMQKA LFDFLKHRFD
GR
ISITRVTA DISLAKRSVL NNPSKRAIIE RSNTRSSLAE VQSEIERIFE
LAR
SLQLVVL DADTINHPAQ LIKTSLAPII VHVKVSSPKV LQRLIKSRGK
SQSK
HLNVQL VAADKLAQCP PEMFDVILDE NQLEDACEHL GEYLEAYWRA
THTSSSTPMT PLLGR
NVGST ALSPYPTAIS GLQSQRMRHS NHSTENSPIE
R
RSLMTSDEN YHNERARKSR NRLSSSSQHS RDHYPLVEED YPDSYQDTYK
PHR
NRGSPGG CSHDSRHRL
Hint: Move your mouse over the sequence to see peptide-specific information.
Legend Within MS mass range Out of MS mass range
Identified RED VIOLET
Not identified BLACK GREY