Channel Proteomes

Protein

Q07652 – Cav2.3

Cav2 Nano-Environments

Protein Details

Full Name Voltage-dependent R-type calcium channel subunit alpha-1E
Sequence Length 2222 AA
Molecular Weight 252,116 Da
Topology transmembrane
Subcellular Location plasma membrane
Biochemical Function ICT
UniProt Q07652

Antibody-Dependent Co-Purification

Solubilization Buffer
Antibody Group CL-91
Anti-CavBeta1
Anti-CavBeta2
Anti-CavBeta3
Anti-CavBeta4

Abundance in Anti-Cav2 APs (relative to Cav2 alpha 1)

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Subtype Preference

Preference for association of Cav2.3 with specific Cav2 alpha 1 subunits.

Not applicable.

Sequence Coverage

Coverage is 35.3% absolute, 71.0% relative. Sequence length is 2222 AA. 736 of 1057 AA found within and 49 of 1165 AA found outside of common MS mass range.

1
51
101
151
201
251
301
351
401
451
501
551
601
651
701
751
801
851
901
951
1001
1051
1101
1151
1201
1251
1301
1351
1401
1451
1501
1551
1601
1651
1701
1751
1801
1851
1901
1951
2001
2051
2101
2151
2201
MALYNPIPVR QNCFTVNRSL FIFGEDNIVR KYAKKLIDWP PFEYMILATI
IANCIVLALE QHLPEDDK
TP MSRRLEKTEP YFIGIFCFEA GIKIVALGFI
FHK
GSYLRNG WNVMDFIVVL SGILATAGTH FNTHVDLRTL RAVRVLRPLK
LVSGIPSLQI VLK
SIMKAMV PLLQIGLLLF FAILMFAIIG LEFYSGKLHR
ACFMNNSGIL EGFDPPHPCG VQGCPAGYEC K
DWIGPNDGI TQFDNILFAV
LTVFQCITME GWTTVLYNTN DALGATWNWL YFIPLIIIGS FFVLNLVLGV
LSGEFAK
ERE RVENRRAFMK LRRQQQIERE LNGYRAWIDK AEEVMLAEEN
K
NSGTSALEV LRRATIKRSR TEAMTRDSSD EHCVDISSVG TPLARASIKS
TK
VDGASYFR HKERLLRISI RHMVKSQVFY WIVLSVVALN TACVAIVHHN
QPQWLTHLLY YAEFLFLGLF LLEMSLK
MYG MGPRLYFHSS FNCFDFGVTV
GSIFEVVWAI FRPGTSFGIS VLR
ALRLLRI FKITKYWASL RNLVVSLMSS
MK
SIISLLFL LFLFIVVFAL LGMQLFGGRF NFNDGTPSAN FDTFPAAIMT
VFQILTGEDW NEVMYNGIR
S QGGVSSGMWS AIYFIVLTLF GNYTLLNVFL
AIAVDNLANA QELTK
DEQEE EEAFNQKHAL QKAKEVSPMS APNMPSIERD
R
RRRHHMSMW EPRSSHLRER RRRHHMSVWE QRTSQLRRHM QMSSQEALNK
EEAPPMNPLN PLNPLSPLNP LNAHPSLYR
R PRPIEGLALG LGLEKCEEER
ISR
GGSLKGD IGGLTSVLDN QRSPLSLGKR EPPWLPRSCH GNCDPTQQET
GGGETVVTFE DR
ARHRQSQR RSRHRRVRTE GKESASASRS RSASQERSLD
EGVSIDGEK
E HEPQSSHRSK EPTIHEEERT QDLRRTNSLM VPRGSGLVGA
LDEAETPLVQ PQPELEVGK
D AALTEQEAEG SSEQALLADV QLDVGRGISQ
SEPDLSCMTT NMDK
ATTEST SVTVAIPDVD PLVDSTVVNI SNKTDGEASP
LK
EAETKEEE EEVEKKKQKK EKRETGKAMV PHSSMFIFST TNPIRKACHY
IVNLR
YFEMC ILLVIAASSI ALAAEDPVLT NSERNKVLRY FDYVFTGVFT
FEMVIK
MIDQ GLILQDGSYF RDLWNILDFV VVVGALVAFA LANALGTNKG
R
DIKTIKSLR VLRVLRPLKT IKRLPKLKAV FDCVVTSLKN VFNILIVYKL
FMFIFAVIAV QLFK
GKFFYC TDSSKDTEKE CIGNYVDHEK NKMEVKGREW
K
RHEFHYDNI IWALLTLFTV STGEGWPQVL QHSVDVTEED RGPSRSNRME
MSIFYVVYFV VFPFFFVNIF VALIIITFQE QGDK
MMEECS LEKNERACID
FAISAKPLTR
YMPQNRHTFQ YRVWHFVVSP SFEYTIMAMI ALNTVVLMMK
YYSAPWTYEL ALK
YLNIAFT MVFSLECVLK VIAFGFLNYF RDTWNIFDFI
TVIGSITEII LTDSK
LVNTS GFNMSFLKLF RAARLIKLLR QGYTIRILLW
TFVQSFK
ALP YVCLLIAMLF FIYAIIGMQV FGNIKLDEES HINRHNNFRS
FFGSLMLLFR
SATGEAWQEI MLSCLGEKGC EPDTTAPSGQ NESERCGTDL
AYVYFVSFIF FCSFLMLNLF VAVIMDNFEY LTR
DSSILGP HHLDEFVRVW
AEYDR
AACGR IHYTEMYEML TLMSPPLGLG KRCPSKVAYK RLVLMNMPVA
EDMTVHFTST LMALIR
TALD IKIAKGGADR QQLDSELQKE TLAIWPHLSQ
K
MLDLLVPMP KASDLTVGKI YAAMMIMDYY KQSKVKKQRQ QLEEQKNAPM
FQR
MEPSSLP QEIISNAKAL PYLQQDPVSG LSGRSGYPSM SPLSPQEIFQ
LACMDPADDG QFQEQQSLVV TDPSSMR
RSF STIRDKRSNS SWLEEFSMER
SSENTYK
SRR RSYHSSLRLS AHRLNSDSGH KSDTHRSGGR ERGRSKERKH
LLSPDVSR
CN SEERGTQADW ESPERRQSRS PSEGRSQTPN RQGTGSLSES
SIPSISDTST PR
RSRRQLPP VPPKPRPLLS YSSLMRHTGG ISPPPDGSEG
GSPLASQALE SNSACLTESS NSLHPQQGQH PSPQHYISEP YLALHEDSHA
SDCGEEETLT FEAAVATSLG R
SNTIGSAPP LRHSWQMPNG HYRRRRLGGL
GLAMMCGAVS DLLSDTEEDD K
C
Hint: Move your mouse over the sequence to see peptide-specific information.
Legend Within MS mass range Out of MS mass range
Identified RED VIOLET
Not identified BLACK GREY